| CAMPEONATO NACIONAL 2021 | ||||
| 1º Fecha | ||||
| 9-mar-2021 | Potosi | Nacional Potosi | 3 | Guaqui, Gutierrez (2) |
| The Strongest | 4 | Villavicencio, Espinoza, Buezo, Massi (P) | ||
| 11-mar-2021 | Cochabamba | Aurora | 0 | |
| Royal Pari | 8 | Melgar (4, 1P), Castillo, Tomianovic, Silves, Jefferson da Silva (P) | ||
| 11-mar-2021 | Tarija | Real Tomayapo | 1 | Isita |
| Always Ready | 0 | |||
| 20-mar-2021 | Oruro | San Jose | 1 | Bilbao |
| Atletico Palmaflor | 3 | Castellon, Santos (P), Blanco | ||
| 20-mar-2021 | Sucre | Independiente Petrolero | 1 | Diaz |
| Oriente Petrolero | 0 | |||
| 21-mar-2021 | Santa Cruz | Blooming | 0 | |
| Guabira | 1 | Abastoflor | ||
| 21-mar-2021 | La Paz | Bolivar | 1 | Ramos |
| Real Potosi | 0 | |||
| 28-mar-2021 | Santa Cruz | Santa Cruz | 0 | |
| Jorge Wilstermann | 2 | Villarroel, Osorio | ||
| 2º Fecha | ||||
| 13-mar-2021 | Montero | Guabira | 3 | Galain, Mina, Vogliotti |
| Bolivar | 1 | Menacho | ||
| 13-mar-2021 | Cochabamba | Jorge Wilstermann | 1 | Chavez |
| Nacional Potosi | 2 | Cuellar (2) | ||
| 13-mar-2021 | Cochabamba | Atletico Palmaflor | 1 | Ubah |
| Santa Cruz | 0 | |||
| 14-mar-2021 | El Alto | Always Ready | 5 | Algarañaz (2), Ovejero, Sanguinetti, Hernandez |
| San Jose | 0 | |||
| 14-mar-2021 | La Paz | The Strongest | 5 | Willie (2), Blackburn, Rafinha, Arrascaita |
| Oriente Petrolero | 2 | Ribera, Montenegro | ||
| 14-mar-2021 | Santa Cruz | Blooming | 2 | Barros, Sanchez |
| Independiente Petrolero | 2 | Aviles, Correa | ||
| 15-mar-2021 | Santa Cruz | Royal Pari | 4 | Siles, Melgar, Castillo, Tomianovic |
| Real Tomayapo | 2 | Vera, Villamil | ||
| 15-mar-2021 | Potosi | Real Potosi | 1 | Bekamenga |
| Aurora | 1 | Alderete | ||
| 3º Fecha | ||||
| 28-mar-2021 | Potosi | Nacional Potosi | 3 | Vargas, Gularte, Cuellar |
| Atletico Palmaflor | 2 | Blanco, Abastoflor | ||
| 1-abr-2021 | Tarija | Real Tomayapo | 0 | |
| Real Potosi | 0 | |||
| 2-abr-2021 | Cochabamba | Aurora | 2 | Alderete, Huayhuata |
| Guabira | 1 | Mina | ||
| 2-abr-2021 | Oruro | San Jose | 0 | |
| Royal Pari | 3 | Orfano, Jefferson da Silva, Amoroso | ||
| 3-abr-2021 | Santa Cruz | Santa Cruz | 2 | Rios (2) |
| Always Ready | 3 | Ovejero, Galindo (P), Algarañaz | ||
| 3-abr-2021 | La Paz | Bolivar | 2 | Gutierrez, Saavedra (P) |
| Blooming | 0 | |||
| 4-abr-2021 | Santa Cruz | Oriente Petrolero | 4 | Niño de Guzman, Vaca, Moreno, Castillo |
| Jorge Wilstermann | 2 | Serginho, Osorio (P) | ||
| 4-abr-2021 | Sucre | Independiente Petrolero | 2 | Correa, Aviles |
| The Strongest | 2 | Sagredo, Reinoso | ||
| 4º Fecha | ||||
| 9-abr-2021 | Santa Cruz | Royal Pari | 3 | Orfano, Amoroso, Jefferson da Silva |
| Santa Cruz | 2 | Reyes (2) | ||
| 9-abr-2021 | Santa Cruz | Blooming | 1 | Ribera |
| Aurora | 0 | |||
| 10-abr-2021 | El Alto | Always Ready | 1 | Sanguinetti |
| Nacional Potosi | 1 | Gularte | ||
| 10-abr-2021 | Cochabamba | Atletico Palmaflor | 2 | Blanco, Santos |
| Oriente Petrolero | 1 | Vaca | ||
| 11-abr-2021 | Montero | Guabira | 0 | |
| Real Tomayapo | 2 | Lima, Nilton | ||
| 11-abr-2021 | Cochabamba | Jorge Wilstermann | 0 | |
| The Strongest | 3 | Reinoso (P), Vaca, Chura | ||
| 11-abr-2021 | Potosi | Real Potosi | 3 | Escalante, Morales, Borda |
| San Jose | 0 | |||
| 12-abr-2021 | La Paz | Bolivar | 1 | Menacho |
| Independiente Petrolero | 0 | |||
| 5º Fecha | ||||
| 23-abr-2021 | Potosi | Nacional Potosi | 2 | Gularte (2, 1P) |
| Royal Pari | 1 | Jefferson da Silva | ||
| 24-abr-2021 | Santa Cruz | Oriente Petrolero | 0 | |
| Always Ready | 0 | |||
| 24-abr-2021 | Oruro | San Jose | 0 | |
| Guabira | 1 | Abastoflor | ||
| 25-abr-2021 | Tarija | Real Tomayapo | 2 | Maldonado, Robles |
| Blooming | 1 | Rojas | ||
| 25-abr-2021 | Sucre | Independiente Petrolero | 5 | Godoy (2), Prost (3) |
| Jorge Wilstermann | 4 | Lizio, Rodriguez, Osorio, Echeverria | ||
| 25-abr-2021 | La Paz | The Strongest | 4 | Sagredo, Reinoso, Wayar, Chura |
| Atletico Palmaflor | 1 | Noir | ||
| 26-abr-2021 | Cochabamba | Aurora | 1 | Torrico |
| Bolivar | 1 | Menacho | ||
| 12-may-2021 | Santa Cruz | Santa Cruz | 4 | Saucedo, Rios, Reyes (2) |
| Real Potosi | 1 | Yecerotte | ||
| 6º Fecha | ||||
| 30-abr-2021 | Santa Cruz | Royal Pari | 0 | |
| Oriente Petrolero | 3 | Dorrego, Vaca, Montenegro | ||
| 1-may-2021 | Cochabamba | Aurora | 3 | Alderete (2), Morales |
| Independiente Petrolero | 0 | |||
| 1-may-2021 | Montero | Guabira | 1 | Hoyos |
| Santa Cruz | 0 | |||
| 2-may-2021 | Potosi | Real Potosi | 1 | Escalante |
| Nacional Potosi | 2 | Torrico, Navarro | ||
| 2-may-2021 | Cochabamba | Atletico Palmaflor | 3 | Noir, Castellon, Saldias |
| Jorge Wilstermann | 1 | Serginho | ||
| 2-may-2021 | La Paz | Bolivar | 2 | Ramos (2) |
| Real Tomayapo | 0 | |||
| 3-may-2021 | Santa Cruz | Blooming | 4 | Latorre, Anangono, Sanchez, Vaca |
| San Jose | 0 | |||
| 11-ago-2021 | El Alto | Always Ready | 2 | Algarañaz, Catuy |
| The Strongest | 1 | Reinoso | ||
| 7º Fecha | ||||
| 7-may-2021 | Santa Cruz | Royal Pari | 1 | Suarez |
| Blooming | 0 | |||
| 8-may-2021 | La Paz | The Strongest | 3 | Reinoso, Chura, Willie |
| Royal Pari | 0 | |||
| 8-may-2021 | Oruro | San Jose | 0 | |
| Bolivar | 5 | Sadiku (2), Ramos (2), Abrego | ||
| 8-may-2021 | Sucre | Independiente Petrolero | 2 | Cristaldo, Godoy |
| Atletico Palmaflor | 0 | |||
| 9-may-2021 | Potosi | Nacional Potosi | 2 | Cabrera, Gularte |
| Guabira | 1 | Sosa | ||
| 9-may-2021 | Cochabamba | Jorge Wilstermann | 5 | Arano, Lizio, Vargas, Alvarez, Rodriguez |
| Always Ready | 2 | Hernandez, Mosquera | ||
| 9-may-2021 | Santa Cruz | Oriente Petrolero | 2 | Castillo, Montenegro |
| Real Potosi | 0 | |||
| 10-may-2021 | Tarija | Real Tomayapo | 1 | Robles |
| Aurora | 2 | Torrico, Sanchez | ||
| 8º Fecha | ||||
| 9-jul-2021 | Tarija | Real Tomayapo | 0 | |
| Independiente Petrolero | 2 | Godoy (2) | ||
| 10-jul-2021 | Potosi | Real Potosi | 1 | Bekamenga |
| The Strongest | 3 | Reinoso (P), Chura, Vaca | ||
| 10-jul-2021 | Cochabamba | Aurora | 3 | Rios (P), Alderete (2, 1P) |
| San Jose | 0 | |||
| 10-jul-2021 | Santa Cruz | Royal Pari | 3 | Ursino, Castillo, Jefferson da Silva |
| Jorge Wilstermann | 2 | Echeverria, Serginho | ||
| 11-jul-2021 | El Alto | Always Ready | 3 | Algarañaz, Arabe (2) |
| Atletico Palmaflor | 2 | Robson, Blanco | ||
| 11-jul-2021 | Montero | Guabira | 1 | Pascua |
| Oriente Petrolero | 1 | Montenegro | ||
| 11-jul-2021 | La Paz | Bolivar | 1 | Abrego |
| Santa Cruz | 1 | Reyes | ||
| 12-jul-2021 | Santa Cruz | Blooming | 2 | Rafinha (2, 1P) |
| Nacional Potosi | 1 | Alvarez (P) | ||
| 9º Fecha | ||||
| 16-jul-2021 | Cochabamba | Jorge Wilstermann | 3 | Echeverria, Añez, Rodriguez |
| Real Potosi | 1 | Candia | ||
| 17-jul-2021 | Santa Cruz | Santa Cruz | 1 | Garcia |
| Aurora | 1 | Alderete (P) | ||
| 17-jul-2021 | Cochabamba | Atletico Palmaflor | 2 | Blanco, Santos (P) |
| Royal Pari | 0 | |||
| 17-jul-2021 | Oruro | San Jose | 1 | Delgadillo |
| Real Tomayapo | 2 | Vera (2) | ||
| 18-jul-2021 | La Paz | The Strongest | 2 | Willie, Reinoso (P) |
| Guabira | 1 | Vogliotti | ||
| 18-jul-2021 | Sucre | Independiente Petrolero | 1 | Prost |
| Always Ready | 2 | Cabrera, Catuy | ||
| 18-jul-2021 | Santa Cruz | Oriente Petrolero | 3 | Ribera, Rioja (A), Vaca |
| Blooming | 0 | |||
| 11-ago-2021 | Potosi | Nacional Potosi | 1 | Gularte |
| Bolivar | 1 | Garcia | ||
| 10º Fecha | ||||
| 20-jul-2021 | Cochabamba | Aurora | 0 | |
| Nacional Potosi | 0 | |||
| 20-jul-2021 | Tarija | Real Tomayapo | 2 | Aleman, Robles |
| Santa Cruz | 1 | Romero | ||
| 21-jul-2021 | Santa Cruz | Royal Pari | 2 | Jefferson da Silva, Orfano |
| Always Ready | 1 | Ramallo | ||
| 21-jul-2021 | Potosi | Real Potosi | 1 | Eguino |
| Atletico Palmaflor | 5 | Lencinas, Candia (A), Santos (2, 1P), Elcarlos | ||
| 21-jul-2021 | Santa Cruz | Blooming | 2 | Garzon, Rafinha |
| The Strongest | 0 | |||
| 22-jul-2021 | Montero | Guabira | 3 | Pascua (2), Peredo |
| Jorge Wilstermann | 2 | Alvarez, Serginho | ||
| 22-jul-2021 | Oruro | San Jose | 1 | Moreira |
| Independiente Petrolero | 3 | Godoy, Chiatti | ||
| 22-jul-2021 | La Paz | Bolivar | 1 | Miranda |
| Oriente Petrolero | 1 | Mojica (P) | ||
| 11º Fecha | ||||
| 24-jul-2021 | El Alto | Always Ready | 2 | Cabrera, Arabe |
| Real Potosi | 1 | Ortega | ||
| 24-jul-2021 | Potosi | Nacional Potosi | 0 | |
| Real Tomayapo | 0 | |||
| 25-jul-2021 | Cochabamba | Atletico Palmaflor | 2 | Santos, Condori |
| Guabira | 1 | Peredo | ||
| 25-jul-2021 | Sucre | Independiente Petrolero | 1 | Siles (A) |
| Royal Pari | 0 | |||
| 25-jul-2021 | La Paz | The Strongest | 3 | Willie (2), Blackburn |
| Bolivar | 1 | Ramos | ||
| 26-jul-2021 | Santa Cruz | Santa Cruz | 5 | Reyes (2), Saucedo (2), Delgadillo (A) |
| San Jose | 0 | |||
| 26-jul-2021 | Cochabamba | Jorge Wilstermann | 2 | Perez (A), Alvarez |
| Blooming | 1 | Farell | ||
| 26-jul-2021 | Santa Cruz | Oriente Petrolero | 1 | Vaca |
| Aurora | 0 | |||
| 12º Fecha | ||||
| 30-jul-2021 | Oruro | San Jose | 0 | |
| Nacional Potosi | 4 | Gularte, Delgadillo (A), Andia, Alvarez | ||
| 30-jul-2021 | Potosi | Real Potosi | 1 | Pastor |
| Royal Pari | 3 | Ursino, Orfano, Amoroso | ||
| 30-jul-2021 | Santa Cruz | Blooming | 1 | Farell |
| Atletico Palmaflor | 1 | Saldias | ||
| 31-jul-2021 | Santa Cruz | Santa Cruz | 2 | Garcia, Reyes (P) |
| Independiente Petrolero | 0 | |||
| 31-jul-2021 | Cochabamba | Aurora | 0 | |
| The Strongest | 1 | Reinoso | ||
| 31-jul-2021 | La Paz | Bolivar | 4 | Fernandez, Miranda, Rey (2) |
| Jorge Wilstermann | 0 | |||
| 1-ago-2021 | Tarija | Real Tomayapo | 0 | |
| Oriente Petrolero | 1 | Baez (A) | ||
| 1-ago-2021 | Montero | Guabira | 0 | |
| Always Ready | 0 | |||
| 13º Fecha | ||||
| 3-ago-2021 | Cochabamba | Atletico Palmaflor | 2 | Castellon, Santos |
| Bolivar | 2 | Granell, Saavedra (P) | ||
| 3-ago-2021 | Sucre | Independiente Petrolero | 2 | Valda (2) |
| Real Potosi | 1 | Ubah | ||
| 4-ago-2021 | El Alto | Always Ready | 5 | Ovejero (2), Cabrera, Rodriguez, Sanguinetti |
| Blooming | 1 | Cabrera | ||
| 4-ago-2021 | Potosi | Nacional Potosi | 2 | Alvarez, Torrico |
| Santa Cruz | 2 | Garcia, Rivero | ||
| 4-ago-2021 | Santa Cruz | Oriente Petrolero | 4 | Moreno (2), Vaca, Nova (A) |
| San Jose | 0 | |||
| 4-ago-2021 | La Paz | The Strongest | 2 | Blackburn, Willie |
| Real Tomayapo | 0 | |||
| 5-ago-2021 | Santa Cruz | Royal Pari | 1 | Jefferson da Silva |
| Guabira | 1 | Mina | ||
| 5-ago-2021 | Cochabamba | Jorge Wilstermann | 2 | Fernandez, Osorio |
| Aurora | 1 | Huayhuata (P) | ||
| 14º Fecha | ||||
| 7-ago-2021 | Santa Cruz | Santa Cruz | 0 | |
| Oriente Petrolero | 0 | |||
| 7-ago-2021 | Oruro | San Jose | 0 | |
| The Strongest | 1 | Reinoso | ||
| 7-ago-2021 | Potosi | Nacional Potosi | 1 | Gularte |
| Independiente Petrolero | 2 | Prost, Aviles | ||
| 8-ago-2021 | Tarija | Real Tomayapo | 1 | Cordoba |
| Jorge Wilstermann | 2 | Rodriguez, Serginho (P) | ||
| 8-ago-2021 | Cochabamba | Aurora | 2 | Sanchez, Toco (A) |
| Atletico Palmaflor | 1 | Castellon | ||
| 8-ago-2021 | La Paz | Bolivar | 0 | |
| Always Ready | 2 | Enoumba, Sanguinetti | ||
| 9-ago-2021 | Montero | Guabira | 3 | Chore, Mina (2) |
| Real Potosi | 0 | |||
| 9-ago-2021 | Santa Cruz | Blooming | 0 | |
| Royal Pari | 1 | Valverde | ||
| 15º Fecha | ||||
| 13-ago-2021 | Sucre | Independiente Petrolero | 2 | Valda, Aviles |
| Guabira | 1 | Leaños | ||
| 13-ago-2021 | Potosi | Real Potosi | 3 | Cabrera (A), Ubah, Escalante |
| Blooming | 1 | Spenhay | ||
| 14-ago-2021 | El Alto | Always Ready | 2 | Algarañaz (2) |
| Aurora | 0 | |||
| 14-ago-2021 | Cochabamba | Atletico Palmaflor | 2 | Elcarlos (2) |
| Real Tomayapo | 0 | |||
| 14-ago-2021 | La Paz | The Strongest | 1 | Martinez |
| Santa Cruz | 2 | Rios, Guzman | ||
| 15-ago-2021 | Santa Cruz | Oriente Petrolero | 0 | |
| Nacional Potosi | 0 | |||
| 15-ago-2021 | Cochabamba | Jorge Wilstermann | 4 | Osorio (2), Rodriguez, Vargas |
| San Jose | 0 | |||
| 15-ago-2021 | Santa Cruz | Royal Pari | 1 | Castillo |
| Bolivar | 1 | Villamil | ||
| 16º Fecha | ||||
| 17-ago-2021 | El Alto | Always Ready | 3 | Algarañaz, Cabrera, Rodriguez |
| Real Tomayapo | 1 | Ferreira | ||
| 17-ago-2021 | Montero | Guabira | 4 | Mosquera (3, 1P), Hurtado |
| Blooming | 2 | Spenhay, Quiroga (A) | ||
| 18-ago-2021 | La Paz | The Strongest | 7 | Blackburn (2), Willie (2), Reinoso, Sotomayor (2) |
| Nacional Potosi | 0 | |||
| 18-ago-2021 | Cochabamba | Atletico Palmaflor | 1 | Santos (P) |
| San Jose | 0 | |||
| 18-ago-2021 | Santa Cruz | Oriente Petrolero | 1 | Moreno |
| Independiente Petrolero | 2 | Godoy, Rodriguez (A) | ||
| 19-ago-2021 | Santa Cruz | Royal Pari | 1 | Castillo (P) |
| Aurora | 0 | |||
| 19-ago-2021 | Potosi | Real Potosi | 0 | |
| Bolivar | 2 | Fernandez, Gutierrez | ||
| 19-ago-2021 | Cochabamba | Jorge Wilstermann | 5 | Franco (A), Rodriguez, Serginho, Ortiz, Osorio |
| Santa Cruz | 1 | Garcia | ||
| 17º Fecha | ||||
| 21-ago-2021 | Oruro | San Jose | 0 | |
| Always Ready | 4 | Catuy, Algarañaz (2), Ramallo | ||
| 21-ago-2021 | Santa Cruz | Oriente Petrolero | 2 | Aponte, Castillo (P) |
| The Strongest | 0 | |||
| 21-ago-2021 | Sucre | Independiente Petrolero | 3 | Correa, Prost (2) |
| Blooming | 0 | |||
| 22-ago-2021 | Potosi | Nacional Potosi | 0 | |
| Jorge Wilstermann | 1 | Serginho | ||
| 22-ago-2021 | Tarija | Real Tomayapo | 1 | Aleman |
| Royal Pari | 4 | Valverde, Castillo, Ribera, Jefferson da Silva | ||
| 22-ago-2021 | La Paz | Bolivar | 6 | Justiniano, Garcia, Bejarano, Montenegro, Saavedra, Abrego |
| Guabira | 0 | |||
| 23-ago-2021 | Santa Cruz | Santa Cruz | 1 | Reyes |
| Atletico Palmaflor | 0 | |||
| 23-ago-2021 | Cochabamba | Aurora | 5 | Sanchez (2), Torrico, Alderete, Barron |
| Real Potosi | 0 | |||
| 18º Fecha | ||||
| 11-sep-2021 | Santa Cruz | Royal Pari | 6 | Jefferson da Silva (2), Ursino, Delgadillo (A), Castillo (2) |
| San Jose | 1 | Añez | ||
| 12-sep-2021 | Potosi | Real Potosi | 1 | Gutierrez |
| Real Tomayapo | 0 | |||
| 12-sep-2021 | Cochabamba | Jorge Wilstermann | 0 | |
| Oriente Petrolero | 1 | Dorrego | ||
| 12-sep-2021 | La Paz | The Strongest | 1 | Willie |
| Independiente Petrolero | 1 | Prost | ||
| 13-sep-2021 | Montero | Guabira | 4 | Mosquera (2P), Quiroga, Mina |
| Aurora | 0 | |||
| 13-sep-2021 | Cochabamba | Atletico Palmaflor | 0 | |
| Nacional Potosi | 0 | |||
| 14-sep-2021 | El Alto | Always Ready | 4 | Sanguinetti, Flores (A), Cabrera, Ovejero |
| Santa Cruz | 0 | |||
| 14-sep-2021 | Santa Cruz | Blooming | 2 | Cabrera, Rafinha (P) |
| Bolivar | 2 | Ramos, Martins | ||
| 19º Fecha | ||||
| 17-sep-2021 | Oruro | San Jose | 0 | |
| Real Potosi | 0 | |||
| 17-sep-2021 | Tarija | Real Tomayapo | 1 | Veizaga |
| Guabira | 1 | Mina | ||
| 18-sep-2021 | Santa Cruz | Santa Cruz | 2 | Reyes (2, 1P) |
| Royal Pari | 1 | Castillo | ||
| 18-sep-2021 | Cochabamba | Aurora | 2 | Maygua, Alderete |
| Blooming | 0 | |||
| 18-sep-2021 | Potosi | Nacional Potosi | 0 | |
| Always Ready | 2 | Enoumba, Rodriguez | ||
| 19-sep-2021 | Sucre | Independiente Petrolero | 2 | Martinez, Prost |
| Bolivar | 1 | Saavedra (P) | ||
| 19-sep-2021 | La Paz | The Strongest | 3 | Arrascaita (2), Reinoso |
| Jorge Wilstermann | 1 | Rodriguez | ||
| 19-sep-2021 | Santa Cruz | Oriente Petrolero | 3 | Vaca (2), Castillo |
| Atletico Palmaflor | 0 | |||
| 20º Fecha | ||||
| 21-sep-2021 | Montero | Guabira | 4 | Mosquera, Mercado, Mina, Vaca |
| San Jose | 0 | |||
| 21-sep-2021 | Potosi | Real Potosi | 3 | Ubah (2), Candia |
| Santa Cruz | 0 | |||
| 22-sep-2021 | Santa Cruz | Blooming | 0 | |
| Real Tomayapo | 1 | Veizaga (P) | ||
| 22-sep-2021 | Cochabamba | Atletico Palmaflor | 0 | |
| The Strongest | 0 | |||
| 22-sep-2021 | La Paz | Bolivar | 5 | Ramos (2), Abrego, Saavedra (P), Miranda |
| Aurora | 1 | Taboada | ||
| 23-sep-2021 | El Alto | Always Ready | 2 | Catuy, Algarañaz |
| Oriente Petrolero | 0 | |||
| 23-sep-2021 | Santa Cruz | Royal Pari | 2 | Jefferson da Silva, Ursino |
| Nacional Potosi | 0 | |||
| 23-sep-2021 | Cochabamba | Jorge Wilstermann | 2 | Osorio, Ortiz |
| Independiente Petrolero | 3 | Correa, Cristaldo, Prost | ||
| 21º Fecha | ||||
| 25-sep-2021 | Oruro | San Jose | 1 | Bilbao |
| Blooming | 2 | Vaca, Rafinha | ||
| 26-sep-2021 | Potosi | Nacional Potosi | 4 | Gularte (2, 1P), Cuellar (2) |
| Real Potosi | 2 | Bekamenga, Yecerotte | ||
| 26-sep-2021 | Tarija | Real Tomayapo | 1 | Ferreira |
| Bolivar | 3 | Ramos, Saavedra, Miranda | ||
| 26-sep-2021 | La Paz | The Strongest | 1 | Blackburn |
| Always Ready | 1 | Uzeda | ||
| 27-sep-2021 | Santa Cruz | Santa Cruz | 3 | Ovando, Reyes, Gonzales |
| Guabira | 0 | |||
| 27-sep-2021 | Sucre | Independiente Petrolero | 3 | Cristaldo, Prost, Godoy |
| Aurora | 0 | |||
| 27-sep-2021 | Santa Cruz | Oriente Petrolero | 2 | Montenegro, Castillo |
| Royal Pari | 4 | Jefferson da Silva, Orfano (2), Saucedo | ||
| 27-sep-2021 | Cochabamba | Jorge Wilstermann | 5 | Seginho (2), Alvarez, Rodriguez, Osorio |
| Atletico Palmaflor | 0 | |||
| 22º Fecha | ||||
| 17-oct-2021 | Cochabamba | Aurora | 1 | Torrico |
| Real Tomayapo | 2 | Robles, Mamani | ||
| 17-oct-2021 | Santa Cruz | Blooming | 3 | Garzon, Spenhay, Rojas |
| Santa Cruz | 1 | Jean | ||
| 18-oct-2021 | Montero | Guabira | 3 | Vogliotti, Mina (2) |
| Nacional Potosi | 2 | Cuellar, Mancilla | ||
| 19-oct-2021 | Potosi | Real Potosi | 2 | Ubah, Yecerotte |
| Oriente Petrolero | 1 | Dorrego (P) | ||
| 19-oct-2021 | Santa Cruz | Royal Pari | 0 | |
| The Strongest | 1 | Martinez | ||
| 19-oct-2021 | La Paz | Bolivar | 4 | Ramos, Bejarano, Miranda, Villamil |
| San Jose | 1 | Velasco (P) | ||
| 20-oct-2021 | El Alto | Always Ready | 0 | |
| Jorge Wilstermann | 0 | |||
| 20-oct-2021 | Cochabamba | Atletico Palmaflor | 0 | |
| Independiente Petrolero | 0 | |||
| 23º Fecha | ||||
| 22-oct-2021 | Oruro | San Jose | 1 | Thomas |
| Aurora | 4 | Huayhuata (P), Taboada, Alderete (P), Torrico | ||
| 22-oct-2021 | Santa Cruz | Oriente Petrolero | 2 | Roca, Caire |
| Guabira | 0 | |||
| 23-oct-2021 | La Paz | The Strongest | 1 | Reinoso |
| Real Potosi | 0 | |||
| 23-oct-2021 | Cochabamba | Jorge Wilstermann | 4 | Rodriguez (2), Serginho, Vargas |
| Royal Pari | 1 | Benegas | ||
| 23-oct-2021 | Potosi | Nacional Potosi | 4 | Andia, Cuellar, Alvarez, Quiroga |
| Blooming | 0 | |||
| 24-oct-2021 | Santa Cruz | Independiente Petrolero | 1 | Correa |
| Real Tomayapo | 0 | |||
| 24-oct-2021 | Cochabamba | Atletico Palmaflor | 0 | |
| Always Ready | 1 | Ramallo | ||
| 24-oct-2021 | Santa Cruz | Santa Cruz | 0 | |
| Bolivar | 3 | Abrego, Ramos, Saavedra | ||
| 24º Fecha | ||||
| 26-oct-2021 | Montero | Guabira | 0 | |
| The Strongest | 0 | |||
| 26-oct-2021 | Potosi | Real Potosi | 2 | Escalante (2) |
| Jorge Wilstermann | 2 | Chavez, Melean | ||
| 27-oct-2021 | El Alto | Always Ready | 2 | Cabrera, Algarañaz |
| Independiente Petrolero | 2 | Cristaldo, Prost | ||
| 27-oct-2021 | Tarija | Real Tomayapo | 1 | Vera |
| San Jose | 0 | |||
| 27-oct-2021 | Santa Cruz | Blooming | 1 | Rafinha (A) |
| Oriente Petrolero | 1 | Dorrego (P) | ||
| 28-oct-2021 | Santa Cruz | Royal Pari | 2 | Siles, Amoroso |
| Atletico Palmaflor | 2 | Terrazas, Olguin | ||
| 28-oct-2021 | La Paz | Bolivar | 4 | Saavedra (P), Ramos, Abrego, Miranda |
| Nacional Potosi | 2 | Gularte, Padilla | ||
| 7-nov-2021 | Cochabamba | Aurora | 4 | Torrico, Huayhuata (P), Moruno, Guzman (A) |
| Santa Cruz | 1 | Saucedo | ||
| 25º Fecha | ||||
| 30-oct-2021 | La Paz | The Strongest | 2 | Blackburn, Willie |
| Blooming | 1 | Orozco | ||
| 30-oct-2021 | Cochabamba | Jorge Wilstermann | 2 | Vargas, Añez |
| Guabira | 1 | Hoyos | ||
| 31-oct-2021 | El Alto | Always Ready | 2 | Ramallo, Rodriguez |
| Royal Pari | 1 | Orfano | ||
| 31-oct-2021 | Potosi | Nacional Potosi | 0 | |
| Aurora | 0 | |||
| 31-oct-2021 | Santa Cruz | Oriente Petrolero | 1 | Aponte |
| Bolivar | 3 | Fernandez, Ramos, Miranda | ||
| 1-nov-2021 | Santa Cruz | Santa Cruz | 2 | Jean, Saucedo (P) |
| Real Tomayapo | 0 | |||
| 1-nov-2021 | Santa Cruz | Independiente Petrolero | 4 | Prost (2), Correa, Gomes |
| San Jose | 0 | |||
| 1-nov-2021 | Cochabamba | Atletico Palmaflor | 0 | |
| Real Potosi | 1 | Escalante | ||
| 26º Fecha | ||||
| 20-nov-2021 | Montero | Guabira | 2 | Mercado, Lencinas (A) |
| Atletico Palmaflor | 0 | |||
| 20-nov-2021 | Cochabamba | Aurora | 1 | Moruno |
| Oriente Petrolero | 2 | Dorrego (2), Suarez | ||
| 20-nov-2021 | Santa Cruz | Royal Pari | 3 | Ursino, Jefferson da Silva, Siles |
| Independiente Petrolero | 1 | Correa (P) | ||
| 21-nov-2021 | Potosi | Real Potosi | 3 | Escalante (2), Yecerotte |
| Always Ready | 2 | Algarañaz, Enoumba | ||
| 21-nov-2021 | La Paz | Bolivar | 0 | |
| The Strongest | 1 | Blackburn | ||
| 21-nov-2021 | Santa Cruz | Blooming | 2 | Garzon, Vaca |
| Jorge Wilstermann | 2 | Rodriguez (P), Lizio | ||
| 22-nov-2021 | Oruro | San Jose | 1 | Prieto |
| Santa Cruz | 2 | Reyes (2) | ||
| 22-nov-2021 | Tarija | Real Tomayapo | 3 | Vera (2), Valencia |
| Nacional Potosi | 0 | |||
| 27º Fecha | ||||
| 26-nov-2021 | Potosi | Nacional Potosi | 7 | Reina, Gularte, Andia, Alvarez, Navarro, Cuellar, Mollo (A) |
| San Jose | 1 | Añez | ||
| 26-nov-2021 | La Paz | The Strongest | 3 | Castro, Willie, Martinez |
| Aurora | 0 | |||
| 26-nov-2021 | Santa Cruz | Oriente Petrolero | 3 | Sanchez (2, 1P), Ribera |
| Real Tomayapo | 1 | Ordoñez | ||
| 27-nov-2021 | El Alto | Always Ready | 6 | Algarañaz (2), Rodriguez, Arabe (3) |
| Guabira | 1 | Mina | ||
| 27-nov-2021 | Cochabamba | Atletico Palmaflor | 3 | Blanco, Gomez, Noir |
| Blooming | 0 | |||
| 27-nov-2021 | Sucre | Independiente Petrolero | 2 | Cristaldo, Ali |
| Santa Cruz | 1 | Gonzales | ||
| 28-nov-2021 | Santa Cruz | Royal Pari | 5 | Ribera, Jefferson da Silva, Melgar, Tomanovic, Castillo |
| Real Potosi | 0 | |||
| 28-nov-2021 | Cochabamba | Jorge Wilstermann | 1 | Torrico |
| Bolivar | 0 | |||
| 28º Fecha | ||||
| 30-nov-2021 | Oruro | San Jose | 0 | |
| Oriente Petrolero | 2 | Rodriguez, Sanchez | ||
| 30-nov-2021 | Santa Cruz | Blooming | 1 | Vaca |
| Always Ready | 2 | Catuy, Algarañaz | ||
| 1-dic-2021 | Santa Cruz | Santa Cruz | 1 | Saucedo (P) |
| Nacional Potosi | 1 | Alvarez (P) | ||
| 1-dic-2021 | Cochabamba | Aurora | 1 | Torrico |
| Jorge Wilstermann | 1 | Serginho (P) | ||
| 1-dic-2021 | La Paz | Bolivar | 3 | Ramos, Saavedra, Fernandez |
| Atletico Palmaflor | 1 | Terrazas | ||
| 2-dic-2021 | Potosi | Real Potosi | 0 | |
| Independiente Petrolero | 5 | Prost (2), Correa (P), Godoy (2) | ||
| 2-dic-2021 | Montero | Guabira | 3 | Mosquera (2, 1P), Mina |
| Royal Pari | 2 | Melgar (2) | ||
| 2-dic-2021 | Tarija | Real Tomayapo | 0 | |
| The Strongest | 0 | |||
| 29º Fecha | ||||
| 4-dic-2021 | Cochabamba | Atletico Palmaflor | 3 | Blanco, Zenteno (A), Vidaurre |
| Aurora | 2 | Zenteno, Torrico | ||
| 4-dic-2021 | Santa Cruz | Oriente Petrolero | 2 | Ribera, Caire (P) |
| Santa Cruz | 0 | |||
| 5-dic-2021 | Sucre | Independiente Petrolero | 2 | Cristaldo, Prost |
| Nacional Potosi | 0 | |||
| 5-dic-2021 | La Paz | The Strongest | 2 | Cardozo, Reinoso |
| San Jose | 0 | |||
| 5-dic-2021 | El Alto | Always Ready | 1 | Catuy |
| Bolivar | 1 | Saavedra | ||
| 5-dic-2021 | Santa Cruz | Royal Pari | 4 | Jefferson da Silva, Melgar, Benegas, Ribera |
| Blooming | 3 | Navarro, Cabrera, Perez | ||
| 5-dic-2021 | Potosi | Real Potosi | 1 | Lovera (P) |
| Guabira | 3 | Mina (3) | ||
| 6-dic-2021 | Cochabamba | Jorge Wilstermann | 3 | Vargas, Alvarez, Melean |
| Real Tomayapo | 0 | |||
| 30º Fecha | ||||
| 10-dic-2021 | Potosi | Nacional Potosi | 1 | Quiroga |
| Oriente Petrolero | 0 | |||
| 10-dic-2021 | La Paz | Bolivar | 2 | Miranda, Fernandez |
| Royal Pari | 0 | |||
| 11-dic-2021 | Tarija | Real Tomayapo | 3 | Lima, Vera, Robles |
| Atletico Palmaflor | 3 | Abastoflor, Gomez, Castellon | ||
| 11-dic-2021 | Oruro | San Jose | 0 | |
| Jorge Wilstermann | 3 | WO | ||
| 11-dic-2021 | Santa Cruz | Blooming | 1 | Rafinha |
| Real Potosi | 0 | |||
| 12-dic-2021 | Montero | Guabira | 2 | Mosquera, Mina |
| Independiente Petrolero | 3 | Amarilla (A), Prost, Godoy | ||
| 12-dic-2021 | Cochabamba | Aurora | 3 | Huayhuata, Montaño, Morales |
| Always Ready | 4 | Cabrera (2), Arce, Algarañaz (P) | ||
| 12-dic-2021 | Santa Cruz | Santa Cruz | 1 | Garcia |
| The Strongest | 0 | |||
| Promocion | ||||
| 15-dic-2021 | Potosi | Real Potosi | 1 | Lovera (P) |
| Universitario | 2 | Brun, Arguello | ||
| 19-dic-2021 | Sucre | Universitario | 2 | L. Gonzales, A. Gonzalez (P) |
| Real Potosi | 0 | |||